Neoself β2GPI Neo-Self Antibody (NS Ab) Test

A simple blood test that detects β2GPI Neo-Self antibodies linked to recurrent miscarriage, implantation failure, and unexplained infertility.

β2GPI Neo-Self Antibodies Test
An advanced immune-related fertility blood test designed to help identify hidden factors that may affect implantation and pregnancy outcomes.

Autoantibodies against β2GPI may interfere with implantation and the development of a healthy pregnancy. Early detection may support timely medical intervention and improved reproductive outcomes.

Why It Matters?
Many fertility cases are still classified as “unexplained,” even after standard investigations.

Immune-related factors such as β2GPI antibodies may affect:

Embryo implantation
Early pregnancy development
Pregnancy maintenance

Quick & Simple Blood Test

Easy, convenient, and minimally invasive
No fasting required
Can be performed at any time during the menstrual cycle

What The Test Detects

This test detects β2GPI (Beta-2 Glycoprotein I) Neo-Self Antibodies, which are associated with immune and clotting responses.

These antibodies may impact:

Implantation success
Embryo attachment to the uterus
Risk of early pregnancy loss

Conditions It May Help Investigate

This test may be recommended for individuals experiencing:

Recurrent pregnancy loss (2 or more miscarriages)
Repeated implantation failure (RIF)
Unexplained infertility
Endometriosis-related fertility issues
Failed IVF/ART cycles despite good-quality embryos

Clinical Insights & Prevalence

Studies suggest the presence of β2GPI antibodies in:

20% of patients with recurrent pregnancy loss (RPL)
30% of patients with endometriosis and RIF
15–20% of patients with infertility

This indicates that immune-related factors may contribute to fertility challenges that standard tests may not detect.

If You Test Positive

If β2GPI Neo-Self Antibodies are detected, your doctor may recommend treatment such as:

Low-Dose Aspirin (LDA)
Heparin (Blood Thinner)

These treatments aim to improve blood flow, support implantation, and increase pregnancy success rates.

Clinical Outcomes (Reported Data)

Implantation Rate (IVF/ART patients)

Without treatment: 21.1%
With Low-Dose Aspirin (LDA): 52.6%

Live Birth Rate (RPL patients)

Without treatment: 50%
With treatment: 87.3%

Clinical studies report improved reproductive outcomes in antibody-positive patients receiving treatment.

Who Should Consider This Test

This test may be suitable for:

Women undergoing IVF or ART treatment
Women with repeated implantation failure
Women with unexplained infertility
Women with endometriosis-related fertility issues
Women with two or more miscarriages

Test Details

Type: Blood test
Preparation: No fasting required
Timing: Can be done at any time during the cycle

Why This Test Matters

Even after standard fertility testing (hormones, scans, embryo grading, or PGT), implantation failure may still occur due to:

Immune dysfunction
Clotting abnormalities
Uterine environment factors
Timing of the implantation window

This test helps identify a potential hidden immune cause.

Disclaimer

This test is intended for informational and diagnostic support purposes and should be interpreted by a qualified healthcare professional. Treatment decisions should be made under medical supervision.

Frequently Asked Questions

1. What are the β2GPI Neo-Self Antibodies?

It is a blood test that detects immune-related antibodies that may affect implantation, increase miscarriage risk, or contribute to unexplained infertility even when other fertility tests are normal.

2. Who should consider this test?

This test is recommended for women with:

Repeated miscarriages (2 or more)
Repeated implantation failure (especially IVF)
Unexplained infertility or endometriosis-related fertility issues

3. What happens if I test positive?

If the antibody is detected, your doctor may recommend treatments such as low-dose aspirin (LDA) or heparin, which have been shown to improve implantation rates and pregnancy outcomes in eligible patients.

Location & Working Hours

MediHope Clinic – Kota Damansara
No. 5-01(GF), Jalan PJU 5/13, Petaling Jaya, 47810 Selangor

🕒 Working Hours:
Monday - Tuesday: 12:00 PM -9:30 PM
Wednesday: Closed
Thursday - Friday: 12:00 PM - 9:00 PM
Saturday: 9:00 AM - 3:00 PM
Sunday: 3:30 PM - 9:30 PM

MediHope Clinic – Bandar Puchong Jaya
105G, Jalan Kenari 23, Bandar Puchong Jaya, 47170 Puchong, Selangor

🕒 Working Hours:
Monday – Sunday: 10:00 AM - 9:30 PM
Saturday: Closed

MediHope Clinic – Cheras C180, Cheras Trader Square
No 32-G, Jalan Dataran Cheras 2, Dataran Perniagaan Cheras, 43200 Balakong, Selangor

🕒 Working Hours:
Monday: 12:00 PM - 9:00 PM
Tuesday: Closed
Wednesday - Friday: 12:00 PM - 9:00 PM
Saturday: 10:00 AM - 9:00 PM
Sunday: 12:00 PM - 5:00 PM

Privacy Protection
All consultations, test results, and medical records are strictly confidential to ensure complete patient privacy.

Terms & Conditions
Open to new and existing patients. Additional treatments recommended by the practitioner will be billed separately.

Please contact Lumirous to book this package.
Customer Service is available weekdays only:
WhatsApp: https://wa.me/+60194004309
✉️ Email: enquiry@lumirous.com